Research Recruitment

Below are research studies currently looking for participants. However, before committing to be a research subject it is important to understand the risks and benefits of participation in research studies and how the research study process works. Read the following articles for a better understanding of research participation.

Participating in Clinical Research

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The Drug Development and Approval Process

By Bertram A. Spilker, MD, PhD
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Current Studies

Research Study for Steadi-One Device

Dr. Philippe Rizek, neurologist/movement disorders specialist, in Mississauga, Canada is conducting a research study to document the efficacy of the Steadi-One on tremor reduction in essential tremor (ET).

The Steadi-One is a battery-free glove worn on an affected arm that is designed to sense and dampen involuntary arm movements.

To be eligible for participation, patients must be at least 18 years of age and have a diagnosed ET. Individuals who are incapable of providing informed consent or who are incapable or unwilling to complete the necessary assessment tasks will be ineligible to participate.

Each participant will only be tested once, and each visit will take approximately two hours.

For patients with a diagnosis of essential tremor interested in participating, please have your family physician or neurologist fax a referral to 905-232-6557.

If you have any questions or need more information please email


The Impact of Cannabis Compound on Essential Tremor

Dr. Fatta Nahab with the Department of Neurosciences at UC San Diego is conducting a research study on Essential Tremor (ET).

You may be eligible if you have been diagnosed with ET or have hand tremors. The purpose of this research study is to determine if a new medication containing cannabis (marijuana) can improve tremors and whether it is safe and effective for use in people with ET.

People with essential tremor will participate in the study for 11 weeks and will undergo a complete neurological examination and psychological testing as a part of the study. In addition, participants will be required to take an oral medication containing cannabis (marijuana). The study will involve up to 9 visits lasting a total of up to 27 hours.

If you are interested in participating, please call (858) 822-3708.


Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders

The Motor Behavior Laboratory of Rutgers University (New Jersey) is looking for individuals with essential tremor, Huntington’s disease, Parkinson’s disease and other movement disorders to participate in a study examining the use of a smartphone application to differentiate patient groups. One laboratory visit of two hours is required and participants will also be asked to use the smartphone application at home for eight weeks.

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The Family Study of Essential Tremor (An NIH-Funded Research Initiative)

Do three living members of your family have essential tremor? Are there at least two members of your family who are NOT affected by essential tremor? The Movement Disorders Division of Yale University is looking for families like this to help with a family study exploring the genetics of essential tremor.

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A Clinical Study to Evaluate CAD-1883 in ET

Cadence-1 is a clinical trial assessing a novel investigational drug, CAD-1883, as a potential treatment for essential tremor.  Enrollment is now open at multiple research centers throughout the US.

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Investigational Drug for People with ET in Upper Limbs

Syneos Health is conducting a study for an investigational drug for people with essential tremor in affecting their upper limbs.

They are looking for volunteers to join this study in the Miami area. If you are between the ages of 18 and 75, you may qualify to participate.

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Study for People with ET in the Upper Limbs

QUEST Research Institute is looking for volunteers to join a new clinical research study being conducted at its research site in the metro-Detroit area. This study will assess an investigational drug for people with essential tremor affecting their upper limbs.

The study will take place in QUEST’s Farmington Hills, MI, office. If you have essential tremor in the upper limbs and are between ages 18 and 75, you may be eligible to participate. 

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Risk Factors Underlying Essential Tremor

Dr. Elan Louis at Yale University is leading an important research initiative. A regional study is being funded by the National Institutes of Health (NIH) and needs participants in the tri-state area of Connecticut, New York and New Jersey. It seeks to understand the environmental factors that lead to essential tremor and Parkinson’s disease (PD).

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The Effect of Sensory Stimulation on Tremor

Researchers at Brigham Young University (BYU) are looking for people with essential tremor to participate in a research study. Headed by Steven Charles, PhD, it is aimed at understanding the effect of sensory stimulation on tremor. BYU campus in Provo, Utah. 

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Understanding the Genetics of Essential Tremor

Researcher’s at McGill University in Montreal, Quebec, Canada are conducting the largest genetics study of essential tremor patients ever. They require 10,000 participants affected by essential tremor. This is an international study and there is no travel involved.

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Brain Activity Measurement Study Using EEG

The essential tremor research team at Columbia University, headed by Dr. Sheng-Han Kuo, is looking for people with essential tremor in the New York City area to study their brain activity using an electroencephalogram (EEG).

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RULET Study of Non-affected Family Members

Yale University is spearheading an important new research initiative. This National Institute of Health (NIH) funded study aims to better understand the lifestyle habits of essential tremor (ET) families. We are calling on the assistance of the ET community and their families to help us with this new research. This is a national study.

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Perampanel Study
Mount Sinai School of Medicine is conducting an essential tremor research trail to find out whether perampanel, a medication marketed for the treatment of seizures, reduces hand tremor in persons with essential tremor. This study is only open to those living in New York City.

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Family Study of ET (FASET II)

Dr. Elan Louis at Yale University and Dr. Lorraine Clark at Columbia University have teamed together for an important research initiative, “FASET II” (family study of ET), to try to identify the genes that are responsible for ET. This is a national study.

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GABA Imaging of Essential Tremor

Dr. Elan Louis and colleagues at Yale University in Connecticut have undertaken a new research initiative. The objective is to use new advanced imaging methods to learn what is happening in the brains of people with ET.

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Brain Tissue Donation

Donate your brain tissue to science and help find the cause of and a cure for essential tremor.

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More Resources

Center for Information and Study on Clinical Research Participation (CISRP)
If you are thinking about joining a clinical study, learn how to evaluate that study, what questions to ask before participating, and what your rights are as a participant.
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This site provides patients, family members and the public with easy access to free information on clinical studies for a wide range of conditions including ET.
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National Institute of Neurological Diseases

This site provides the most recent biomedical research publication concerning human subjects.
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